Abstract Intratumor heterogeneity of tumor clones and an immunosuppressive microenvironment in cancer ecosystems contribute to inherent difficulties for tumor treatment. Recently. chimeric antigen receptor (CAR) T-cell therapy has been successfully applied in the treatment of B-cell malignancies. underscoring its great potential in antitumor therapy. https://macorners.shop/product-category/graduation-teddy-bear/