Purpose: We report a patient with severe multi-organ dysfunction of unknown origin who presented with bilateral orbital and chorioretinal manifestations that led to the diagnosis of Erdheim-Chester Disease (ECD). Observations: ECD is a rare. histiocytic. proliferative disorder characterized by multi-systemic organ involvement that has historically lacked effective therapy. https://www.roneverhart.com/Toshiba-AL13SX-AL13SXB30EN-300GB-15K-RPM-SAS-12Gb-s-512n-128MB-2-5-Hard-Drive/